The Missouri Department of Transportation will begin bridge work Saturday east of Palmyra.
MoDOT will close the South River Bridge on Missouri 168 beginning Saturday morning between County Road 339 and Route JJ.
Crews will replace the bridge deck with a new concrete layer. Alternate routes of travel will be available over US 61 at Palmyra to reach areas north of the bridge, and at US 61 at Hannibal to get to areas south of the bridge.
Some roads will remain open to residential traffic only.
The bridge is expected to be closed for up to 10 days.