Cardinals vs. Reds Predictions & Picks: Odds, Moneyline, Spread - May 22

Monday's game features the St. Louis Cardinals (21-27) and the Cincinnati Reds (19-27) squaring off at Great American Ball Park in what should be a tight matchup, with a projected 4-2 victory for the Cardinals according to our computer prediction. First pitch is at 6:40 PM ET on May 22.

The Cardinals will look to Jordan Montgomery (2-6) versus the Reds and Brandon Williamson.

Cardinals vs. Reds Game Info & Odds

• When: Monday, May 22, 2023 at 6:40 PM ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: BSOH
• Live Stream: Watch this game on Fubo!

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Cardinals vs. Reds Score Prediction

Our pick for this game is Cardinals 4, Reds 3.

Total Prediction for Cardinals vs. Reds

• Total Prediction: Under 10 runs

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Read More About This Game

Cardinals Performance Insights

• The Cardinals have played as the favorite in four of their past 10 games and have won two of those contests.
• In its last 10 games with a total, St. Louis and its opponents have combined to hit the over six times.
• There has not been a spread set for any of the Cardinals' last 10 games.
• This season, the Cardinals have won 11 out of the 24 games, or 45.8%, in which they've been favored.
• St. Louis has a record of 2-4 when favored by -190 or more by sportsbooks this season.
• The bookmakers' moneyline implies a 65.5% chance of a victory for the Cardinals.
• St. Louis has scored the fifth-most runs in the majors this season with 245.
• The Cardinals' 4.25 team ERA ranks 15th across all MLB pitching staffs.

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Cardinals Schedule